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Benzyl Alcohol

Published: July 26, 2026Updated: August 25, 2026

Benzyl Alcohol is a topical medication primarily used to treat head lice infestations (pediculosis). It works as a pediculicide, killing lice by suffocation after penetrating their exoskeleton. This medication is approved for use in adults and children as young as 6 months old.

Quick summary

Topical treatment for head lice infestations that works by suffocating the parasites.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

ATC
P03AX11
RxNorm
1363
Generic
Benzyl Alcohol
Class
atc-p03
Brands
Shing-Releev, Ivy Dry Super Continuous Spray, Itch-X, Ivy-Dry Cream, Zilactin-L Cold Sore Liquid, Ulesfia, Zilactin Cold Sore
Availability
otc
Pregnancy
B
Lactation
caution
Half-life (h)
0
Onset (min)
5
Duration (h)
2
Routes
topical, oral
Forms
lotion, cream, spray, liquid, gel
Regions
United States, Canada, Europe, Australia
Monitoring
application site irritation, presence of live lice after treatment

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Dosage and administration

adult (standard)topical solution
Usual dose
5-10% concentration applied to affected area
Maximum
consult physician
Frequency
2-3 times daily as needed
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard
pediatric (standard)topical solution
Usual dose
5% concentration applied to affected area
Maximum
consult physician
Frequency
2-3 times daily as needed
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard
geriatric (standard)topical solution
Usual dose
5-10% concentration applied to affected area
Maximum
consult physician
Frequency
2-3 times daily as needed
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard

Overdose information

Important overdose information
Toxic dose: Single dose of approximately 10g or more may cause serious toxicity in adults
Chronic overdose: Prolonged or excessive use can lead to accumulation causing metabolic acidosis and central nervous system depression
Immediate actions
Supportive care, airway management, breathing and circulatory support, activated charcoal if ingestion within 1 hour
Antidote
None - supportive care only(Supportive care is the primary treatment; no specific antidote exists)
Poison Control: 1-800-222-1222

Special Populations

10 groups
⚠

pregnancy

first trimester
caution
FDA Category
C
Dose Adjustment

avoid extensive use

Key Recommendations

use only on small areas of intact skin if benefits outweigh risks

Monitor

regular prenatal checkups

Use with caution and monitor for adverse effects.

⚠

pregnancy

third trimester
caution
FDA Category
C
Dose Adjustment

minimize use

Key Recommendations

avoid large area application or prolonged use

Monitor

fetal monitoring as appropriate

Use with caution and monitor for adverse effects.

⚠

lactation

breastfeeding
caution
FDA Category
C
Dose Adjustment

avoid application to breast area

Key Recommendations

do not apply to breasts before breastfeeding; wash thoroughly if used elsewhere

Monitor

monitor infant for unusual symptoms

Use with caution and monitor for adverse effects.

✗

pediatric_age

neonates
contraindicated
FDA Category
C
Dose Adjustment

absolute contraindication

Key Recommendations

do not use in premature infants or newborns; risk of gasping syndrome

Monitor

none due to contraindication

Use of this medication in this population requires careful consideration of risks and benefits.

⚠

pediatric_age

infants and children
caution
FDA Category
C
Dose Adjustment

use smallest effective amount

Key Recommendations

avoid use on broken skin or large body areas in children under 2 years

Monitor

observe for signs of irritation or systemic absorption

Use with caution and monitor for adverse effects.

✓

geriatric

elderly
safe
FDA Category
C
Dose Adjustment

no adjustment needed

Key Recommendations

standard topical use is appropriate

Monitor

monitor for skin irritation

✓

renal_impairment

mild to moderate
safe
FDA Category
C
Dose Adjustment

no adjustment for topical use

Key Recommendations

standard topical application is generally safe

Monitor

none specific

⚠

renal_impairment

severe
caution
FDA Category
C
Dose Adjustment

use with caution

Key Recommendations

avoid extensive or occlusive dressings over treated areas

Monitor

monitor renal function

Use with caution and monitor for adverse effects.

⚠

hepatic_impairment

mild to moderate
caution
FDA Category
C
Dose Adjustment

use sparingly

Key Recommendations

avoid large area application

Monitor

monitor for signs of accumulation

Use with caution and monitor for adverse effects.

⚠

hepatic_impairment

severe
caution
FDA Category
C
Dose Adjustment

avoid extensive use

Key Recommendations

use only on small areas of intact skin

Monitor

liver function monitoring

Use with caution and monitor for adverse effects.

Statistics and clinical data

prescribingFDA
2023

Commonly prescribed since

Value:1980s

General prescribing information for topical benzyl alcohol preparations

drug_classFDA
2023

Drug class

Value:Topical Anesthetic/Antipruritic

Classification as a topical anesthetic agent

usageMedical guidelines
2023

Common uses

Value:Treatment of itching, pain relief from minor burns, insect bites, and skin irritations

Common therapeutic uses in topical preparations

administrationFDA
2023

Route of administration

Value:Topical

Method of application for benzyl alcohol products

Treatment of head lice (Pediculus humanus capitis) infestations. May also have preservative properties in various pharmaceutical formulations.

Acts as a topical ectoparasiticide; penetrates the lice exoskeleton and suffocates them by blocking their respiratory system. The exact mechanism is not fully specified but is believed to involve physical suffocation rather than neurotoxic effects.

For external use only on scalp hair and scalp. Should not be ingested or applied to broken skin. May cause mild skin irritation. Safety in children under 6 months has not been established. A second treatment may be needed after 7 days to kill newly hatched lice. Avoid contact with eyes.

Contraindications

Conditions and patient states where this medication should be avoided or used with caution.

Do not use (1)

ABSOLUTEhypersensitivity

Known allergy to this medication or its components

Use caution (1)

RELATIVEpregnancy

Consult healthcare provider for benefits vs risks assessment

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy