Betaine / Folic Acid / Mecobalamin / Pyridoxine
This multi-ingredient supplement combines betaine with B vitamins (folic acid, mecobalamin, and pyridoxine) to support homocysteine metabolism. It is primarily used for conditions associated with elevated homocysteine levels, B-vitamin deficiencies, and certain types of anemia, as well as supporting neurological health.
A combination supplement of betaine and B vitamins used to lower homocysteine levels, treat deficiencies, and support nerve health.
Key facts at a glance
- RxNorm
- 1144760
- Generic
- Betaine / Folic Acid / Mecobalamin / Pyridoxine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment and prevention of hyperhomocysteinemia, megaloblastic and pernicious anemia, peripheral neuropathy, and B-vitamin deficiency states. May also be used as an adjunct in neurological conditions associated with methylmalonic acid accumulation.
Betaine acts as a methyl donor in the conversion of homocysteine to methionine. Folic acid and mecobalamin (methylcobalamin) support the remethylation pathway of homocysteine metabolism, while pyridoxine (B6) aids in transsulfuration pathways. Together, they facilitate efficient homocysteine clearance and support DNA synthesis, red blood cell formation, and nerve function.
Generally well-tolerated but may cause mild GI symptoms in some individuals. Folic acid can mask B12 deficiency symptoms; adequate B12 status should be confirmed. Not a substitute for addressing underlying causes of elevated homocysteine. Patients should inform their healthcare provider of all supplements and medications being taken.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy