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Betamethasone

Published: July 26, 2026Updated: July 26, 2026

Betamethasone is a topical corticosteroid used to treat inflammatory and itchy skin conditions such as eczema, psoriasis, and dermatitis by reducing inflammation and suppressing the immune response.

Quick summary

A topical corticosteroid that relieves inflammation, itching, and redness associated with various skin conditions.

Medically reviewed by WellAlly Editorial TeamLast reviewed July 26, 2026Editorial policy

Key facts at a glance

ATC
A07EA04
RxNorm
1514
Generic
Betamethasone
Class
atc-a07
Brands
Gentacalm, Genone, Betavet, Otomax, Enstilar, Sernivo, Del-Beta, Diprolene, Wynzora, Luxiq, Duotic, Osurnia, Celestone Soluspan, Taclonex, GentaVed
Availability
rx
Lactation
unknown
Routes
topical, otic, ophthalmic, oral
Forms
gel, ointment, cream, solution, tablet, spray, suspension
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Dosage and administration

adult (standard)tablet
Usual dose
0.6mg twice daily
Maximum
consult physician
Frequency
every 12 hours
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard
pediatric (standard)tablet
Usual dose
0.3mg twice daily
Maximum
consult physician
Frequency
every 12 hours
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard
geriatric (standard)tablet
Usual dose
0.6mg daily
Maximum
consult physician
Frequency
once daily
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard

Overdose information

Important overdose information
Toxic dose: Single dose exceeding 100mg may cause significant corticosteroid toxicity
Chronic overdose: prolonged use exceeding recommended doses leads to Cushing's syndrome and adrenal suppression
Immediate actions
discontinue medication, initiate supportive care, monitor vital signs and electrolytes
Antidote
no specific antidote(supportive care is mainstay of treatment; no antidote available)
Poison Control: 1-800-222-1222

Special Populations

7 groups
⚠

pregnancy

first trimester
caution
FDA Category
C
Dose Adjustment

avoid if possible, use lowest effective dose

Key Recommendations

avoid use during first trimester unless benefits clearly outweigh risks

Monitor

regular fetal monitoring, ultrasound assessments

Use with caution and monitor for adverse effects.

⚠

pregnancy

third trimester
caution
FDA Category
C
Dose Adjustment

single course may be given for fetal lung maturation

Key Recommendations

betamethasone course (two doses 24h apart) indicated for preterm labor to accelerate fetal lung maturity

Monitor

fetal growth monitoring, blood glucose monitoring in mother

Use with caution and monitor for adverse effects.

⚠

lactation

breastfeeding
caution
FDA Category
N
Dose Adjustment

use lowest effective dose

Key Recommendations

betamethasone can pass into breast milk, monitor infant for adrenal suppression

Monitor

monitor infant for signs of adrenal suppression, poor weight gain

Use with caution and monitor for adverse effects.

⚠

pediatric_age

children
caution
FDA Category
N
Dose Adjustment

use lowest effective dose for shortest duration

Key Recommendations

avoid prolonged use in children due to growth suppression, monitor growth velocity

Monitor

regular growth monitoring, adrenal function assessment

Use with caution and monitor for adverse effects.

⚠

geriatric

elderly
caution
FDA Category
N
Dose Adjustment

start at lower end of dosing range

Key Recommendations

increased risk of osteoporosis, diabetes, hypertension, cataracts; use with caution

Monitor

bone density monitoring, blood pressure, blood glucose, eye exams

Use with caution and monitor for adverse effects.

⚠

renal_impairment

moderate to severe
caution
FDA Category
N
Dose Adjustment

may require dose adjustment in severe impairment

Key Recommendations

use with caution, monitor fluid and electrolyte balance

Monitor

renal function monitoring, electrolytes, fluid balance

Use with caution and monitor for adverse effects.

⚠

hepatic_impairment

moderate to severe
caution
FDA Category
N
Dose Adjustment

may require dose reduction

Key Recommendations

corticosteroids are metabolized in liver, use with caution in hepatic impairment

Monitor

liver function tests, adrenal function monitoring

Use with caution and monitor for adverse effects.

Statistics and clinical data

prescribingFDA
2023

First FDA approval

Value:1950s

First approval date for betamethasone formulations

drug_classWHO
2023

Drug class

Value:Corticosteroid

Pharmacological classification of betamethasone

usageMedical guidelines
2023

Common uses

Value:Inflammatory and autoimmune conditions

Primary therapeutic applications including skin disorders, allergic reactions, and rheumatic conditions

brand_countFDA
2023

Available brand formulations

Value:15 brands

Number of branded formulations including Gentacalm, Genone, Betavet, Otomax, Enstilar, Sernivo, Del-Beta, Diprolene, Wynzora, Luxiq, Duotic, Osurnia, Celestone Soluspan, Taclonex, GentaVed

Treats corticosteroid-responsive dermatoses including atopic dermatitis, eczema, psoriasis, seborrheic dermatitis, and allergic skin reactions that cause inflammation, itching, and redness.

As a corticosteroid, betamethasone reduces inflammation by suppressing immune cell activity and decreasing the production of inflammatory mediators in the skin, thereby relieving symptoms of redness, itching, and swelling.

For external use only on intact skin; avoid use on open wounds, broken skin, or infected areas. Do not use for prolonged periods or on large body areas without medical supervision as it may cause skin thinning. Not effective for viral, fungal, or bacterial infections alone. Use exactly as prescribed by your healthcare provider.

Contraindications

Conditions and patient states where this medication should be avoided or used with caution.

Do not use (1)

ABSOLUTEhypersensitivity

Known allergy to this medication or its components

Use caution (1)

RELATIVEpregnancy

Consult healthcare provider for benefits vs risks assessment

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy