Betamethasone / Calcipotriene
Betamethasone/Calcipotriene is a topical combination medication used to treat plaque psoriasis. It combines a corticosteroid (betamethasone) with a vitamin D analog (calcipotriene) to reduce inflammation, itching, and abnormal skin cell growth associated with this chronic skin condition.
A topical treatment combining a corticosteroid and vitamin D analog for plaque psoriasis.
Key facts at a glance
- RxNorm
- 690419
- Generic
- Betamethasone / Calcipotriene
- Class
- multi-ingredient
- Brands
- Enstilar, Wynzora, Taclonex
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
This medication is primarily indicated for the treatment of plaque psoriasis, a chronic autoimmune condition causing thick, scaly, red patches on the skin. It may be prescribed when psoriasis affects moderate to large areas of the body.
Betamethasone is a topical corticosteroid that works by reducing inflammation, suppressing immune activity, and constricting blood vessels in the skin. Calcipotriene is a vitamin D analog that helps regulate skin cell differentiation and proliferation, slowing the rapid turnover of skin cells characteristic of psoriasis. Together, they address both the inflammatory and proliferative components of psoriasis.
This medication is for topical use only and should not be applied to the face, groin, or armpits unless directed by a healthcare provider. It may increase the risk of skin atrophy (thinning) with prolonged use. Patients should avoid prolonged use beyond recommended durations and follow their prescribing healthcare provider's instructions carefully. Pregnant women should consult their doctor before use.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy