Betamethasone / Florfenicol / Terbinafine
This combination medication combines a corticosteroid (betamethasone), antibiotic (florfenicol), and antifungal (terbinafine) in a single topical formulation. It is designed to treat inflammatory skin conditions with concurrent or suspected bacterial and fungal infections. The three active ingredients work synergistically to address multiple components of complex dermatological conditions.
A topical combination medication for treating inflammatory skin conditions complicated by bacterial and fungal infections.
Key facts at a glance
- RxNorm
- 2704734
- Generic
- Betamethasone / Florfenicol / Terbinafine
- Class
- multi-ingredient
- Brands
- Osurnia
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
This medication is typically used for inflammatory skin disorders such as severe dermatitis, eczema, or allergic skin reactions that have become complicated by secondary bacterial or fungal infections. It may also be prescribed for conditions like otitis externa (ear infections) involving multiple pathogens, and other dermatological conditions requiring broad-spectrum antimicrobial and anti-inflammatory treatment.
Betamethasone provides anti-inflammatory and immunosuppressive effects by inhibiting inflammatory mediators and reducing immune cell activity. Florfenicol is a broad-spectrum antibiotic that inhibits bacterial protein synthesis, effective against many gram-positive and gram-negative bacteria. Terbinafine works as an antifungal by inhibiting ergosterol synthesis, disrupting fungal cell membrane integrity. Together, they address inflammation, bacterial infection, and fungal infection simultaneously.
This medication is typically for topical use only and should not be used on open wounds or broken skin unless specifically directed by a healthcare provider. Prolonged use of corticosteroids may cause skin thinning. Avoid use in patients with known hypersensitivity to any components. Treatment duration should be as prescribed to minimize resistance development. Consult a healthcare professional before use during pregnancy or breastfeeding.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy