Bevacizumab-bvzr
Bevacizumab-Bvzr is a biosimilar medication referencing Avastin (bevacizumab), belonging to the anti-angiogenesis drug class. It works by inhibiting vascular endothelial growth factor (VEGF), a protein that promotes blood vessel formation in tumors. This medication is used in combination with other therapies to treat various cancers.
Bevacizumab-Bvzr is a biosimilar cancer treatment that inhibits blood vessel growth to tumors by targeting VEGF.
Key facts at a glance
- RxNorm
- 2268037
- Generic
- Bevacizumab-Bvzr
- Class
- pin-variant
- Brands
- Zirabev
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treats various cancers including metastatic colorectal cancer, non-small cell lung cancer, renal cell carcinoma, glioblastoma, ovarian/fallopian tube/primary peritoneal cancer, cervical cancer, and hepatocellular carcinoma. Used when prescribed for its anti-angiogenic properties.
As a monoclonal antibody biosimilar, it binds to vascular endothelial growth factor (VEGF), preventing VEGF from interacting with its receptors on endothelial cells. This inhibits tumor angiogenesis—the process of forming new blood vessels that feed tumors—slowing tumor growth and spread.
Administered by intravenous infusion. May cause serious side effects including gastrointestinal perforation, wound healing complications, hemorrhage, arterial thromboembolism, hypertension, proteinuria, and infusion reactions. Contraindicated in pregnancy. Patients should be monitored for signs of these complications. As a biosimilar, it has demonstrated no clinically meaningful differences from the reference product.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy