Bictegravir / Emtricitabine / Tenofovir Alafenamide
Bictegravir/emtricitabine/tenofovir alafenamide is a single-tablet combination antiretroviral medication used to treat HIV-1 infection in adults and children weighing at least 14 kg. It combines three drugs that work together to suppress the HIV virus, allowing the immune system to recover and reducing the risk of HIV-related complications.
A complete once-daily HIV treatment regimen combining three antiretroviral agents in a single tablet.
Key facts at a glance
- RxNorm
- 1996259
- Generic
- Bictegravir / Emtricitabine / Tenofovir Alafenamide
- Class
- multi-ingredient
- Brands
- Biktarvy
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of HIV-1 infection in treatment-naive adults and children (weighing at least 14 kg), as well as virologically suppressed patients switching from a stable antiretroviral regimen. Not indicated for HIV-2 or HBV infection.
This combination targets HIV at multiple stages: bictegravir inhibits the integrase enzyme, preventing viral DNA integration into host cells; emtricitabine and tenofovir alafenamide are nucleoside/nucleotide reverse transcriptase inhibitors that block the conversion of viral RNA into DNA, reducing viral replication.
Should not be used in patients with severe hepatic or renal impairment. May cause immune reconstitution syndrome, lactic acidosis, and hepatomegaly. Discontinuation may result in HBV exacerbation in co-infected patients. Resistance testing is recommended before initiating therapy.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy