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Bile Salts / Pancreatin / Pepsin

Published: July 27, 2026Updated: August 28, 2026

Bile Salts/Pancreatin/Pepsin A is a combination digestive enzyme supplement that aids in the breakdown and absorption of fats, proteins, and carbohydrates. This medication is typically used by individuals with digestive disorders or pancreatic insufficiency who have difficulty absorbing nutrients from food. It works by replacing or supplementing the body's natural digestive enzymes and bile salts that may be deficient.

Quick summary

A digestive enzyme combination medication that helps people with enzyme deficiencies absorb nutrients from food.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 28, 2026Editorial policy

Key facts at a glance

RxNorm
1008996
Generic
Bile Salts / Pancreatin / Pepsin A
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

This medication is used to treat conditions involving digestive enzyme deficiency, including chronic pancreatitis, cystic fibrosis-related pancreatic insufficiency, post-surgical malabsorption following gastric or intestinal surgery, and bile salt deficiency. It may also be used in elderly patients with reduced digestive enzyme production.

The combination works synergistically: Pepsin A begins protein digestion in the stomach's acidic environment, while pancreatin (containing lipase, amylase, and protease) continues digestion of fats, proteins, and carbohydrates in the small intestine. Bile salts emulsify dietary fats, increasing the surface area for lipase enzymes to work more effectively.

This medication should be taken with meals and adequate water. Effectiveness depends on proper timing with food intake. Patients with pork allergies should avoid products containing pancreatin (typically porcine-derived). Do not crush or chew enteric-coated formulations. Consult a healthcare provider before use if pregnant, breastfeeding, or taking other digestive medications.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy