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Bioallethrin / Piperonyl Butoxide

Published: July 27, 2026Updated: August 28, 2026

Bioallethrin with Piperonyl Butoxide is an insecticidal combination used primarily in pest control products rather than as a human therapeutic medication. Bioallethrin is a synthetic pyrethroid that acts on insect nervous systems, while Piperonyl Butoxide enhances its effectiveness by inhibiting enzymes that would otherwise break down the insecticide. This combination is commonly found in household insecticides, pet flea collars, and some topical anti-lice treatments.

Quick summary

A topical insecticidal combination used to treat parasitic infections like head lice and control fleas, working by targeting insect nervous systems.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 28, 2026Editorial policy

Key facts at a glance

RxNorm
814380
Generic
Bioallethrin / Piperonyl Butoxide
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Primarily used for treatment of head lice (pediculosis) and crab lice infestations, as well as flea control in veterinary settings. Also found in household insecticide products for flying and crawling insects.

Bioallethrin is a synthetic pyrethroid that disrupts sodium channels in insect nerve membranes, causing paralysis and death. Piperonyl Butoxide acts as a synergist by inhibiting cytochrome P450 enzymes in insects that would normally metabolize and detoxify pyrethroids, thereby enhancing insecticidal efficacy.

For topical use only; avoid contact with eyes, nose, and mouth. Not for use on infants or individuals with known pyrethroid sensitivity. Environmental Protection Agency regulations govern indoor residential use. Professional pest control applications may have different regulatory requirements.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy