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Anthrax Vaccine

Published: July 26, 2026Updated: September 3, 2026

Biothrax is a brand-name vaccine used to prevent anthrax disease, a serious bacterial infection caused by Bacillus anthracis. It is approved for both pre-exposure prophylaxis in adults at high risk of exposure and post-exposure prophylaxis following suspected or confirmed anthrax exposure. The vaccine works by stimulating the immune system to develop protection against the anthrax bacterium.

Quick summary

Biothrax is a vaccine used to protect against anthrax disease in high-risk individuals or following potential exposure.

Medically reviewed by WellAlly Editorial TeamLast reviewed September 3, 2026Editorial policy

Key facts at a glance

RxNorm
404894
Generic
Biothrax
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Biothrax is indicated for active immunization against anthrax disease in adults aged 18-65 years. It is used for pre-exposure prophylaxis in individuals at high risk of contact with anthrax spores (such as certain laboratory workers and military personnel) and for post-exposure prophylaxis in combination with antibiotic therapy following suspected or confirmed exposure to Bacillus anthracis.

Biothrax is an inactivated vaccine that contains protective antigen (PA) derived from Bacillus anthracis. The vaccine stimulates the immune system to produce antibodies against the protective antigen component of anthrax toxins. These antibodies help the body recognize and fight the anthrax bacterium if exposure occurs, though the exact immunological mechanisms are not fully characterized.

Biothrax is administered by intramuscular injection. Common side effects may include injection site reactions such as pain, redness, or swelling, as well as headache, fatigue, or muscle aches. The vaccine is not intended for treatment of active anthrax infection. It should be used with caution in individuals with compromised immune systems. A complete vaccination series and timing of doses are important for optimal protection; consult prescribing information for specific scheduling.

Official drug label

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Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed September 3, 2026. · Read our editorial policy