Guaifenesin and Dextromethorphan
Biotussin is a brand-name cough preparation historically used for temporary relief of cough symptoms associated with colds and respiratory infections. It typically contains a cough suppressant (such as dextromethorphan) and sometimes an expectorant (guaifenesin) to help loosen mucus. Availability of specific Biotussin formulations varies by region and time period.
Biotussin is an over-the-counter brand used for temporary cough and cold symptom relief.
Key facts at a glance
- RxNorm
- 995842
- Generic
- Biotussin
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporarily relieves cough due to minor throat and bronchial irritation as may occur with colds. May also help relieve chest congestion when formulated with an expectorant.
When containing dextromethorphan, it acts on the cough center in the brain to suppress the cough reflex. When containing guaifenesin, it helps loosen and thin mucus in the airways to make coughs more productive.
Formulations vary by manufacturer and region—always check the specific active ingredients on the product label. Do not use in children under certain ages without consulting a healthcare provider. Avoid combining with other cough medications containing similar ingredients. Consult a healthcare provider if cough persists beyond 7 days or is accompanied by fever, rash, or persistent headache.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed September 3, 2026. · Read our editorial policy