Bismuth Subcitrate
Bismuth Subcitrate is a gastric protective agent used to treat peptic ulcers and gastritis by forming a protective coating over the stomach lining and exhibiting antibacterial properties.
Bismuth Subcitrate protects the stomach lining and fights H. pylori bacteria to treat ulcers and gastritis.
This medication carries a boxed (black box) warning — the strongest type of FDA warning. Review the full prescribing information before use.
Key facts at a glance
- ATC
- A02BX05
- RxNorm
- 47181
- Generic
- Bismuth Subcitrate
- Class
- atc-a02
- Brands
- Pylera
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet, capsule
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of peptic ulcers (gastric and duodenal), gastritis, and dyspepsia. Commonly used as part of combination therapy for eradicating Helicobacter pylori infection.
Forms a protective complex with ulcer bases, creating a barrier against gastric acid and pepsin. Also exhibits antibacterial activity against H. pylori and may stimulate mucosal defense mechanisms.
May cause temporary darkening of tongue and stool (benign effect). Generally well-tolerated for short-term use. Not recommended for patients with severe renal impairment. Use during pregnancy requires careful risk-benefit assessment. Should be used as part of combination therapy for H. pylori, not as monotherapy.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy