Bismuth Subgallate / Phthalylsulfathiazole
Bismuth Subgallate/Phthalylsulfathiazole is a combination medication used to treat infectious diarrhea and bacterial gastrointestinal infections. The bismuth component provides astringent and protective effects on the gastrointestinal lining, while the sulfonamide antibiotic phthalylsulfathiazole acts directly against susceptible bacteria in the gut. This medication has been used particularly in regions where it remains available for treatment of dysentery and related conditions.
A combination of an astringent and antibiotic used to treat bacterial diarrhea and gastrointestinal infections.
Key facts at a glance
- RxNorm
- 1007393
- Generic
- Bismuth Subgallate / Phthalylsulfathiazole
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of acute and chronic diarrhea caused by bacterial infections, including bacillary dysentery and other gastrointestinal infections caused by susceptible organisms.
Phthalylsulfathiazole is a sulfonamide antibiotic that inhibits bacterial growth in the intestinal tract by interfering with folic acid synthesis. Bismuth subgallate acts as an astringent, providing protective coating and reducing intestinal inflammation.
This medication may cause discoloration of stool (black discoloration from bismuth). Sulfonamides can cause allergic reactions, particularly in patients with sulfa sensitivity. Adequate fluid intake is essential during treatment. Should be used with caution in patients with renal impairment. Note: Sulfonamides have been largely replaced by other antibiotics in many countries due to resistance patterns and availability of alternatives.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy