Bismuth Subsalicylate / Calcium Carbonate
This combination medication pairs an antacid with a stomach-protecting agent to address multiple digestive symptoms simultaneously. Calcium carbonate works to neutralize excess stomach acid providing relief from heartburn and acid indigestion, while bismuth subsalicylate helps protect the stomach lining and reduce symptoms like nausea and diarrhea. It is commonly used by adults experiencing overlapping symptoms of acid reflux and general gastrointestinal upset.
A dual-action OTC medication combining an antacid with a stomach-protecting agent to relieve heartburn, acid indigestion, and mild gastrointestinal discomfort.
Key facts at a glance
- RxNorm
- 690610
- Generic
- Bismuth Subsalicylate / Calcium Carbonate
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treats symptoms of heartburn, acid indigestion, sour stomach, nausea, and mild diarrhea. May also help with stomach upset associated with these conditions.
Calcium carbonate neutralizes stomach acid through an acid-base reaction, raising pH to reduce acidity and irritation. Bismuth subsalicylate exerts protective effects on the stomach lining and may help reduce bacterial growth in the gut while decreasing fluid secretion in the intestines.
Avoid use in individuals allergic to salicylates (including aspirin). Use caution if taking blood thinners or other salicylate-containing products due to increased risk of bleeding. Not recommended for children or teenagers recovering from viral infections due to Reye's syndrome risk. Consult a healthcare provider before use if pregnant, breastfeeding, or taking other medications.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy