Bismuth Subsalicylate
Bizengri (zenocutuzumab) is a bispecific monoclonal antibody designed to target HER2 and HER3 receptors on cancer cells. It is FDA-approved for treating adults with NRG1 fusion-positive pancreatic adenocarcinoma and NRG1 fusion-positive other solid tumors, making it a targeted therapy option for cancers driven by NRG1 gene fusions.
Bizengri is a targeted antibody therapy for NRG1 fusion-positive pancreatic cancer and other solid tumors.
Key facts at a glance
- RxNorm
- 2699596
- Generic
- Bizengri
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Bizengri is indicated for the treatment of adults with NRG1 fusion-positive pancreatic adenocarcinoma and NRG1 fusion-positive other solid tumors. It is used when the cancer has been confirmed to have an NRG1 gene fusion, which drives tumor growth.
Bizengri is a bispecific antibody that binds to both HER2 and HER3 receptors on cancer cells. By simultaneously blocking these receptors, it inhibits the signaling pathways that promote cancer cell growth and survival in NRG1 fusion-positive tumors.
Bizengri is administered via intravenous infusion. Common side effects may include fatigue, musculoskeletal pain, nausea, and infusion-related reactions. Patients should be monitored for cardiac effects and other adverse reactions during treatment. Treatment should be supervised by healthcare providers experienced in cancer therapy.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed September 3, 2026. · Read our editorial policy