Bismuth Potassium Citrate
Bkemv (eculizumab-axge) is a brand-name biosimilar medication that works as a complement inhibitor. It is used to treat paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS), and generalized myasthenia gravis in patients who are not adequately controlled with other therapies.
Bkemv is a complement inhibitor biosimilar used to treat rare blood and neuromuscular disorders including PNH, aHUS, and myasthenia gravis.
Key facts at a glance
- RxNorm
- 2706353
- Generic
- Bkemv
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treats paroxysmal nocturnal hemoglobinuria (PNH) to reduce hemolysis, atypical hemolytic uremic syndrome (aHUS) to control complement-mediated thrombotic microangiopathy, and refractory generalized myasthenia gravis in anti-acetylcholine receptor antibody positive adults.
As a complement inhibitor, Bkemv is a monoclonal antibody that binds to complement protein C5, preventing its cleavage into C5a and C5b. This blocks the terminal complement pathway, inhibiting complement-mediated destruction of red blood cells in PNH and endothelial damage in aHUS.
Requires REMS certification due to meningococcal infection risk. Patients must be vaccinated before starting treatment and monitored for signs of infection. Administered as intravenous infusion. May increase risk of serious infections including sepsis and meningitis. Should not be used in patients with unresolved serious infections.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed September 3, 2026. · Read our editorial policy