Boceprevir
Boceprevir is a direct-acting antiviral agent that was used to treat chronic hepatitis C virus (HCV) genotype 1 infection in adults with compensated liver disease. It was always used in combination with peginterferon alfa and ribavirin, and was administered as part of triple therapy regimens.
Boceprevir is a hepatitis C protease inhibitor used in triple therapy regimens that has since been largely replaced by newer, more effective antiviral medications.
Key facts at a glance
- ATC
- J05AP03
- RxNorm
- 1102129
- Generic
- Boceprevir
- Class
- atc-j05
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- capsule
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of chronic hepatitis C virus (HCV) genotype 1 infection in adult patients with compensated liver disease who had not been previously treated or who had failed prior interferon-based therapy.
Boceprevir is a NS3/4A protease inhibitor that directly inhibits the replication of the hepatitis C virus by blocking a key enzyme needed for viral protein processing and viral replication.
Boceprevir must always be used in combination with peginterferon alfa and ribavirin; it should not be used as monotherapy. Treatment response is monitored using hepatitis C viral load testing at specific time points. Boceprevir has been discontinued from the market and replaced by newer direct-acting antivirals with improved efficacy and fewer side effects.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy