Ibandronate
Boniva (ibandronate sodium) is a bisphosphonate medication used to treat and prevent osteoporosis in postmenopausal women. It works by inhibiting bone-resorbing cells called osteoclasts, which helps increase bone mineral density and reduce fracture risk. The medication is available as a monthly oral tablet or quarterly intravenous injection.
Boniva is a bisphosphonate used to treat and prevent osteoporosis in postmenopausal women by reducing bone loss and increasing bone density.
Key facts at a glance
- RxNorm
- 541684
- Generic
- Boniva
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Boniva is indicated for the treatment and prevention of osteoporosis in postmenopausal women. It helps reduce the risk of vertebral and hip fractures by maintaining or improving bone strength.
Boniva belongs to the bisphosphonate class of drugs. It inhibits osteoclast activity, the cells responsible for breaking down bone tissue. This reduces bone resorption and helps shift the balance toward bone formation, thereby increasing bone mineral density over time.
Oral tablets must be taken first thing in the morning on an empty stomach with a full glass of plain water. Patients should remain upright (sitting or standing) for at least 60 minutes after taking and avoid eating, drinking, or taking other medications during this time. Boniva is not recommended for patients with severe kidney impairment, low blood calcium, or known hypersensitivity to bisphosphonates. Rare side effects may include esophageal irritation, jawbone problems (osteonecrosis), and atypical femur fractures with long-term use.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed September 3, 2026. · Read our editorial policy