Botulinum Neurotoxin D Immune Fab2, Equine
Botulinum Neurotoxin D Immune Fab2, Equine is an antitoxin product containing F(ab')2 immunoglobulin fragments derived from equine (horse) serum. It is used for the treatment and post-exposure prophylaxis of botulism poisoning caused by Clostridium botulinum type D neurotoxin. The equine-derived antibodies work by binding to and neutralizing the botulinum toxin, preventing it from exerting its effects on the nervous system.
An equine-derived antitoxin used to treat and prevent botulism caused by type D botulinum neurotoxin.
Key facts at a glance
- RxNorm
- 1722700
- Generic
- Botulinum Neurotoxin D Immune Fab2, Equine
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment and post-exposure prophylaxis of foodborne, wound, or inhalational botulism caused by botulinum neurotoxin type D. Typically administered when botulism is suspected based on clinical presentation or known exposure.
Equine F(ab')2 immunoglobulin fragments bind specifically to botulinum neurotoxin type D, neutralizing its activity and preventing the toxin from binding to presynaptic nerve terminals. This blocks the inhibition of acetylcholine release at the neuromuscular junction, thereby preventing the descending flaccid paralysis characteristic of botulism.
As an equine-derived product, there is a risk of hypersensitivity reactions including anaphylaxis, particularly in patients with prior exposure to equine proteins. Skin testing may be recommended before administration. F(ab')2 fragments have lower immunogenicity than whole antibodies but serum sickness remains possible. Should be administered as early as possible after toxin exposure for optimal efficacy.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy