Encorafenib
Braftovi (encorafenib) is a prescription targeted therapy medication known as a BRAF inhibitor used to treat certain cancers with specific genetic mutations. It is primarily indicated for melanoma and colorectal cancer that test positive for BRAF V600E or V600K mutations, and is typically used in combination with other medications such as cetuximab.
Braftovi is an oral targeted therapy for BRAF-mutated melanoma and colorectal cancer, working by blocking cancer cell growth signals.
Key facts at a glance
- RxNorm
- 2049112
- Generic
- Braftovi
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Braftovi is used to treat adults with unresectable or metastatic melanoma with BRAF V600E or V600K mutations, and in combination with cetuximab for adults with metastatic colorectal cancer with BRAF V600E mutation.
As a BRAF inhibitor, Braftovi blocks the activity of mutated BRAF proteins, which are abnormally active in certain cancer cells and drive uncontrolled cell growth and division.
Braftovi is a brand-name medication with no generic equivalent currently available. Common side effects may include fatigue, nausea, and skin reactions. Regular monitoring and genetic testing for BRAF mutations are required before and during treatment. It should only be used as directed by an oncologist and may interact with other medications.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed September 3, 2026. · Read our editorial policy