Bremelanotide Acetate
Bremelanotide Acetate is a synthetic melanocortin peptide analog administered as a subcutaneous injection for the treatment of hypoactive sexual desire disorder (HSDD) in premenopausal women. It acts on melanocortin receptors in the central nervous system to enhance sexual desire and arousal.
A melanocortin receptor agonist injection used by premenopausal women to treat low sexual desire.
Key facts at a glance
- RxNorm
- 2176311
- Generic
- Bremelanotide Acetate
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Bremelanotide is FDA-approved for treating acquired, generalized hypoactive sexual desire disorder (HSDD) in premenopausal women. It is used as needed before anticipated sexual activity and is not indicated for HSDD caused by medical conditions, psychiatric disorders, or relationship problems.
As a non-selective agonist of melanocortin receptors (primarily MC3 and MC4), bremelanotide activates pathways involved in sexual desire and arousal. It is not a hormone but modulates neurochemical signaling in brain regions responsible for sexual response.
Administered via subcutaneous injection in the abdomen or thigh at least 45 minutes before sexual activity. Common side effects include nausea, flushing, headache, and injection site reactions. Patients should limit use to 8 doses per month and avoid use in patients with uncontrolled hypertension or cardiovascular disease due to potential blood pressure increases.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy