Methohexital
Brevital (methohexital) is a short-acting barbiturate anesthetic used primarily for the induction and maintenance of general anesthesia during surgical procedures. It acts as a central nervous system depressant, producing rapid sedation and unconsciousness. This medication is typically administered in hospital settings by trained anesthesiologists and is particularly useful for short surgical procedures where quick recovery is desired.
Brevital is a short-acting barbiturate anesthetic used for inducing general anesthesia and sedation during medical procedures.
Key facts at a glance
- RxNorm
- 227282
- Generic
- Brevital
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Brevital is used for induction of general anesthesia, maintenance of anesthesia during short surgical procedures, sedation for diagnostic procedures, and occasionally for treatment of status epilepticus when other options are not available.
Brevital works by enhancing the effects of GABA (gamma-aminobutyric acid) in the brain, leading to increased inhibition of neuronal firing and resulting in sedation, hypnosis, and anesthesia.
Brevital should only be administered by qualified anesthesia providers in controlled settings with appropriate monitoring and resuscitation equipment available. It carries risks including respiratory depression, hypotension, and potential for dependence. Patients should disclose their complete medical history, including any allergies, liver problems, or substance use disorders, before treatment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed September 3, 2026. · Read our editorial policy