Lisocabtagene Maraleucel
Breyanzi is a personalized CAR-T cell therapy that reprograms a patient's own immune cells to recognize and attack cancer cells. It is used to treat adults with certain types of relapsed or refractory large B-cell lymphoma who have undergone two or more prior treatments. This therapy involves extracting the patient's T cells, genetically engineering them, and infusing them back into the patient.
Breyanzi is a CD19-directed CAR-T cell therapy for relapsed/refractory large B-cell lymphoma.
Key facts at a glance
- RxNorm
- 2479141
- Generic
- Breyanzi
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Breyanzi is approved for adults with relapsed or refractory large B-cell lymphoma after two or more lines of systemic therapy, including diffuse large B-cell lymphoma (DLBCL), primary mediastinal large B-cell lymphoma, high-grade B-cell lymphoma, and DLBCL arising from follicular lymphoma.
Breyanzi is a CD19-directed genetically modified autologous T-cell immunotherapy. The patient's T cells are collected and modified with a receptor (CAR) that targets the CD19 antigen found on the surface of B cells, enabling the engineered cells to identify and destroy cancer cells.
Breyanzi carries a risk of serious side effects including cytokine release syndrome (CRS) and neurological toxicities. It should only be administered at certified healthcare facilities with appropriate monitoring and management capabilities. Patients require close monitoring following infusion, typically for several days to assess for potential adverse reactions.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed September 3, 2026. · Read our editorial policy