Brimonidine / Carbachol
Brimonidine/Carbachol is an ophthalmic combination medication used primarily to reduce intraocular pressure in patients with glaucoma or ocular hypertension. This combination works through complementary mechanisms: brimonidine decreases aqueous humor production while carbachol increases outflow through the trabecular meshwork. The dual-action approach provides more effective pressure reduction than either agent alone.
An eye drop combination for glaucoma that lowers pressure by decreasing fluid production and increasing fluid drainage.
Key facts at a glance
- RxNorm
- 2736928
- Generic
- Brimonidine / Carbachol
- Class
- multi-ingredient
- Brands
- Yuvezzi
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of elevated intraocular pressure in open-angle glaucoma and ocular hypertension. May be used when monotherapy is insufficient for adequate pressure control.
Brimonidine is an alpha-2 adrenergic agonist that reduces aqueous humor production. Carbachol is a cholinergic agonist that increases uveoscleral outflow and causes pupillary constriction. Together, they provide complementary pressure-lowering effects.
For ophthalmic use only. May cause temporary blurred vision, eye irritation, or redness. Systemic absorption is possible; monitor for side effects including hypotension or bradycardia. Contraindicated in patients with angle-closure glaucoma. Avoid contact lens wear immediately after administration.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy