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Brimonidine / Timolol

Published: July 27, 2026Updated: August 28, 2026

Brimonidine/Timolol is an ophthalmic combination medication used to reduce elevated intraocular pressure in patients with glaucoma or ocular hypertension. It combines two pressure-lowering agents that work through different mechanisms to decrease fluid production in the eye.

Quick summary

An eye drop combination that lowers eye pressure in glaucoma patients by combining two different pressure-reducing agents.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 28, 2026Editorial policy

Key facts at a glance

RxNorm
597142
Generic
Brimonidine / Timolol
Class
multi-ingredient
Brands
Combigan
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Treatment of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension who require additional intraocular pressure reduction.

Combines an alpha-2 adrenergic agonist (brimonidine) with a beta-blocker (timolol). Both agents reduce aqueous humor production in the eye, providing greater intraocular pressure reduction than either component alone.

For ophthalmic use only. May cause side effects such as eye irritation, dry mouth, blurred vision, or fatigue. Systemic absorption can occur; inform your doctor of any respiratory conditions, heart conditions, or depression before use. Wait at least 5 minutes between applying different eye medications.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy