Bromazepam
Bromazepam is a benzodiazepine medication primarily used to treat anxiety disorders, anxiety associated with depression, and panic attacks. It works by enhancing the effect of GABA, a neurotransmitter that reduces brain activity, producing a calming effect. Due to risks of dependence and tolerance, it is typically prescribed for short-term use.
Bromazepam is a benzodiazepine used short-term to treat anxiety and panic disorders by enhancing calming brain chemicals.
Key facts at a glance
- ATC
- N05BA08
- RxNorm
- 1749
- Generic
- Bromazepam
- Class
- atc-n05
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Dosage and administration
- Usual dose
- 1.5-3mg twice daily
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- Not recommended
- Maximum
- consult physician
- Frequency
- N/A
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 1.5mg twice daily
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
Overdose information
Special Populations
8 groupspregnancy
first trimesteravoid if possible
avoid use during pregnancy unless benefits outweigh risks
regular fetal monitoring
Use of this medication in this population requires careful consideration of risks and benefits.
pregnancy
third trimesteravoid
avoid use near delivery due to risk of neonatal sedation and withdrawal
monitor newborn for respiratory depression and withdrawal symptoms
Use of this medication in this population requires careful consideration of risks and benefits.
lactation
breastfeedingavoid
avoid breastfeeding during treatment due to excretion in breast milk
monitor infant for excessive sedation
Use of this medication in this population requires careful consideration of risks and benefits.
geriatric
elderlyreduce dose by 50%
use lowest effective dose, start at half adult dose, monitor for falls and cognitive impairment
regular assessment of cognitive function and balance
Use with caution and monitor for adverse effects.
pediatric_age
children adolescentsnot recommended
not recommended for use in children under 18 years due to insufficient safety data
not applicable
Use of this medication in this population requires careful consideration of risks and benefits.
renal_impairment
moderate to severereduce dose by 25-50%
use with caution in patients with creatinine clearance below 30 mL/min
monitor renal function and adjust dose accordingly
Use with caution and monitor for adverse effects.
hepatic_impairment
moderate to severereduce dose by 25-50%
use with caution due to metabolism in liver, avoid in severe hepatic impairment
monitor liver function tests
Use with caution and monitor for adverse effects.
alcohol_users
concurrent useavoid combination
avoid concurrent alcohol use due to additive CNS depressant effects
monitor for excessive sedation and respiratory depression
Use of this medication in this population requires careful consideration of risks and benefits.
Statistics and clinical data
Drug class
Benzodiazepine anxiolytic class of medications
Mechanism of action
Enhances GABAergic neurotransmission
Common uses
Therapeutic indications for bromazepam
Average half-life
Elimination half-life range 10-30 hours
Treatment of anxiety disorders, anxiety associated with depressive symptoms, and panic attacks. May also be used for preoperative anxiety or alcohol withdrawal symptoms.
Binds to benzodiazepine receptors on the GABA-A receptor complex, enhancing the inhibitory effects of GABA neurotransmitter. This reduces neuronal excitability and produces sedative, anxiolytic, and muscle relaxant effects.
Should only be used short-term (typically 2-4 weeks) due to risk of dependence, tolerance, and withdrawal symptoms. May cause drowsiness and impair cognitive function; avoid alcohol and operating machinery. Not recommended for long-term use or in patients with a history of substance abuse.
Contraindications
Conditions and patient states where this medication should be avoided or used with caution.
Do not use (1)
Known allergy to this medication or its components
Use caution (1)
Consult healthcare provider for benefits vs risks assessment
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy