Bromelains / Papain
Bromelains and Papain is a combination of proteolytic (protein-digesting) enzymes derived from pineapple stems and papaya fruit. This multi-ingredient supplement is primarily used to support digestive function and as an anti-inflammatory agent for various inflammatory conditions.
Bromelains/Papain combines two proteolytic enzymes to aid protein digestion and reduce inflammation.
Key facts at a glance
- RxNorm
- 1007352
- Generic
- Bromelains / Papain
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
This combination is used to support digestive health, particularly for breaking down dietary proteins. It is also commonly used for reducing inflammation associated with sinusitis, sports injuries, and arthritis. Some formulations are used topically to assist with wound healing and skin conditions.
Both bromelain and papain are proteolytic enzymes that break down proteins into smaller peptides and amino acids, facilitating digestion. Their anti-inflammatory effects are thought to result from inhibition of pro-inflammatory compounds and reduction of fluid buildup at inflammatory sites.
Individuals with allergies to pineapple or papaya should avoid this product. It may increase bleeding risk and should be used cautiously with blood thinners or before surgical procedures. Those with bleeding disorders or stomach ulcers should consult a healthcare provider before use. May be taken with meals for digestive support or between meals for anti-inflammatory effects.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy