Bromodiphenhydramine
Bromodiphenhydramine is a first-generation antihistamine medication used to treat allergic conditions such as hay fever, allergic rhinitis, and skin allergies. It works by blocking histamine H1 receptors, reducing symptoms like sneezing, itching, and runny nose. Due to its sedating properties, it may also be used as a sleep aid.
Bromodiphenhydramine is a sedating antihistamine used to treat allergies and related symptoms.
Key facts at a glance
- ATC
- R06AA01
- RxNorm
- 19759
- Generic
- Bromodiphenhydramine
- Class
- atc-r06
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- solution
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of seasonal and perennial allergic rhinitis, allergic skin reactions, hay fever symptoms (sneezing, itching, watery eyes, runny nose), and cold symptoms. May also be used for motion sickness and as a short-term sleep aid.
Bromodiphenhydramine is an H1 receptor antagonist that blocks histamine, a chemical released during allergic reactions. As a first-generation antihistamine, it also has anticholinergic properties and crosses the blood-brain barrier, causing sedative effects.
May cause drowsiness and impaired coordination; avoid driving or operating machinery. Should be used with caution in elderly patients, those with glaucoma, urinary retention, or heart conditions. Should not be combined with alcohol or other CNS depressants. First-generation antihistamines are generally not recommended for prolonged use due to anticholinergic side effects.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy