Bromodiphenhydramine / Codeine
Bromodiphenhydramine/codeine is a combination medication that pairs an antihistamine with an opioid cough suppressant. The antihistamine component helps relieve allergy symptoms such as runny nose, sneezing, and itchy eyes, while the codeine component acts on the brain's cough reflex to reduce coughing. This medication is typically prescribed for short-term relief of cough and upper respiratory symptoms associated with allergies or the common cold.
An antihistamine/opioid combination used to relieve cough and allergy symptoms.
Key facts at a glance
- RxNorm
- 214323
- Generic
- Bromodiphenhydramine / Codeine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporary relief of cough and upper respiratory symptoms associated with allergies, the common cold, or other respiratory conditions. May also help with runny nose, sneezing, and itchy eyes.
Bromodiphenhydramine blocks histamine H1 receptors to reduce allergic symptoms and has sedative properties. Codeine binds to opioid receptors in the brain to suppress the cough reflex and may provide mild pain relief.
This medication may cause drowsiness; avoid alcohol and operating machinery. Codeine carries risk of dependence with prolonged use. Not recommended for children; contraindicated in certain populations. May interact with other CNS depressants. Use only as prescribed for short-term relief.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy