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Brompheniramine / Codeine / Guaifenesin

Published: July 27, 2026Updated: August 28, 2026

Brompheniramine/codeine/guaifenesin is a combination medication used to treat cough and cold symptoms. It combines an antihistamine, an opioid cough suppressant, and an expectorant to address multiple symptoms including coughing, congestion, and mucus buildup. This medication is typically prescribed for respiratory conditions accompanied by productive cough.

Quick summary

A combination cough and cold medication that suppresses cough, relieves congestion, and helps loosen mucus.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 28, 2026Editorial policy

Key facts at a glance

RxNorm
1008059
Generic
Brompheniramine / Codeine / Guaifenesin
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Temporary relief of symptoms associated with the common cold, allergies, or respiratory infections, including cough, nasal congestion, sneezing, runny nose, and chest congestion.

Brompheniramine blocks histamine receptors to reduce allergic symptoms; codeine suppresses the cough reflex in the brain; and guaifenesin thins and loosens mucus in the airways to make coughs more productive.

Contains codeine, an opioid that carries risk of dependence, drowsiness, and respiratory depression. Avoid alcohol and operating machinery. Not recommended for children under 18 years old. May interact with other sedatives or opioid medications. Consult a healthcare provider before use if pregnant, breastfeeding, or taking other medications.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy