Brompheniramine / Codeine / Phenylephrine
This combination medication contains three active ingredients to address multiple cold and allergy symptoms. Brompheniramine provides antihistamine relief for runny nose and sneezing, codeine acts as a cough suppressant, and phenylephrine works as a decongestant to reduce nasal swelling. It is typically prescribed for short-term relief of upper respiratory symptoms associated with colds, allergies, or sinus infections.
A multi-symptom cold medication combining an antihistamine, cough suppressant, and decongestant for relief of cough, congestion, and allergic symptoms.
Key facts at a glance
- RxNorm
- 690647
- Generic
- Brompheniramine / Codeine / Phenylephrine
- Class
- multi-ingredient
- Brands
- Brovex PBC, M-End PE
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporary relief of cough, nasal congestion, runny nose, sneezing, and itchy/watery eyes associated with upper respiratory infections, allergies, or sinus conditions. Often used when multiple symptoms are present and require combined treatment.
Brompheniramine blocks histamine H1 receptors to reduce allergic responses; codeine suppresses the cough reflex in the brain's medulla oblongata; phenylephrine constricts blood vessels in nasal passages to reduce swelling and congestion. The three ingredients work on different pathways to address cough, allergy, and congestion symptoms simultaneously.
Contains codeine, an opioid with risk of dependence, drowsiness, and respiratory depression. Should not be combined with alcohol, sedatives, or other CNS depressants. Not recommended for children under 12 years old. May cause drowsiness—avoid driving until aware of effects. Use only as prescribed; do not exceed recommended dose or duration. Consult healthcare provider before use if pregnant, breastfeeding, or taking other medications.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy