Brompheniramine / Codeine / Phenylpropanolamine
This combination medication contains three active ingredients: an antihistamine (brompheniramine), an opioid cough suppressant (codeine), and a decongestant (phenylpropanolamine). It is used to temporarily relieve cough and cold symptoms including nasal congestion, sneezing, and runny nose associated with allergies or upper respiratory infections.
A combination cough and cold medication that addresses multiple symptoms through antihistamine, opioid cough suppressant, and decongestant ingredients.
Key facts at a glance
- RxNorm
- 214327
- Generic
- Brompheniramine / Codeine / Phenylpropanolamine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporary relief of cough, nasal congestion, sneezing, runny nose, and other upper respiratory symptoms associated with allergies, common cold, or rhinitis. May be used for productive or dry coughs where symptom relief is needed.
Brompheniramine blocks histamine receptors to reduce allergic symptoms; codeine acts on the cough center in the brain to suppress the cough reflex; phenylpropanolamine constricts blood vessels in the nasal passages to reduce nasal congestion and swelling.
Contains codeine, an opioid that carries risk of dependence, drowsiness, and respiratory depression. Should not be used in children under 12 or in those with certain medical conditions. Avoid alcohol and operating machinery. May interact with other medications. Use only as directed for short-term relief. FDA black box warning for opioid risks.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy