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Brompheniramine / Dextromethorphan / Guaifenesin / Phenylephrine

Published: July 27, 2026Updated: August 28, 2026

This combination medication provides multi-symptom relief for upper respiratory conditions by addressing cough, congestion, and allergy symptoms simultaneously. It contains an antihistamine, cough suppressant, expectorant, and decongestant to target multiple symptoms of colds, allergies, and sinus congestion. This medication is typically used by adults and children seeking relief from cough, stuffy nose, chest congestion, and sneezing.

Quick summary

A multi-ingredient cold and allergy medication that relieves cough, congestion, and runny nose through combined antihistamine, cough suppressant, expectorant, and decongestant actions.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 28, 2026Editorial policy

Key facts at a glance

RxNorm
1008002
Generic
Brompheniramine / Dextromethorphan / Guaifenesin / Phenylephrine
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Temporary relief of cold, flu, and allergy symptoms including cough due to minor throat irritation, nasal congestion, sinus congestion, chest congestion, and runny nose associated with these conditions.

Brompheniramine blocks histamine to reduce allergic symptoms; dextromethorphan suppresses the cough reflex in the brain; guaifenesin thins and loosens mucus in the airways; phenylephrine constricts blood vessels in the nasal passages to reduce swelling and congestion.

May cause drowsiness; avoid operating machinery or driving until you know how this medication affects you. Do not use if taking an MAOI or within 14 days of stopping one. Consult a doctor before use if you have heart disease, high blood pressure, thyroid problems, diabetes, glaucoma, or breathing problems. Do not crush or chew sustained-release formulations.

Official drug label

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Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy