Skip to content

Brompheniramine / Dextromethorphan / Guaifenesin / Phenylpropanolamine

Published: July 27, 2026Updated: August 28, 2026

This multi-symptom cold and cough medication combines four active ingredients to provide relief from respiratory infections and allergic conditions. It addresses congestion, coughing, mucus buildup, and runny nose simultaneously. This combination is typically used by adults and older children experiencing multiple cold or allergy symptoms at once.

Quick summary

A combination cold medication that relieves congestion, cough, and allergy symptoms through four complementary active ingredients.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 28, 2026Editorial policy

Key facts at a glance

RxNorm
820044
Generic
Brompheniramine / Dextromethorphan / Guaifenesin / Phenylpropanolamine
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Treats common cold symptoms, allergic rhinitis, and sinus congestion including nasal stuffiness, runny nose, sneezing, itchy/watery eyes, cough, and chest congestion. Used when multiple symptoms are present simultaneously.

Brompheniramine blocks histamine to reduce sneezing and runny nose; dextromethorphan suppresses the cough reflex in the brain; guaifenesin thins and loosens mucus in the airways; phenylpropanolamine constricts blood vessels in nasal passages to reduce swelling and congestion.

May cause drowsiness; avoid operating machinery or driving until you know how it affects you. Do not use with alcohol or other sedatives. Not recommended for children under 6 years old without medical supervision. Consult a healthcare provider if symptoms persist beyond 7-10 days or if you have high blood pressure, heart disease, thyroid disorders, diabetes, or glaucoma. May interact with MAO inhibitors and other medications.

Official drug label

WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy