Brompheniramine / Diphenhydramine
Brompheniramine/Diphenhydramine is a combination of two first-generation antihistamines used to treat allergic symptoms such as sneezing, runny nose, itchy eyes, and nasal congestion. This multi-ingredient formulation provides dual antihistamine action for enhanced relief of seasonal allergies and common cold symptoms.
A combination antihistamine used to relieve allergy and cold symptoms like sneezing, runny nose, and itchy eyes.
Key facts at a glance
- RxNorm
- 834773
- Generic
- Brompheniramine / Diphenhydramine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Relief of allergic rhinitis, hay fever, common cold symptoms, runny nose, sneezing, itchy/watery eyes, and nasal congestion. Often found in over-the-counter cold and allergy medications.
Both brompheniramine and diphenhydramine are H1 receptor antagonists that block histamine from binding to receptors, reducing allergic symptoms. They also have anticholinergic properties that help dry nasal secretions.
May cause drowsiness; avoid alcohol and operating machinery. Not recommended for children under 6 unless directed by a physician. May interact with other sedatives or anticholinergic medications. Consult healthcare provider if pregnant, breastfeeding, or taking other medications.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy