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Brompheniramine / Guaifenesin / Phenylephrine

Published: July 27, 2026Updated: August 28, 2026

This multi-ingredient medication combines an antihistamine (brompheniramine), an expectorant (guaifenesin), and a decongestant (phenylephrine) to address multiple cold, flu, and allergy symptoms simultaneously. It is typically used to temporarily relieve nasal congestion, sinus pressure, chest congestion, and bothersome symptoms like runny nose and sneezing.

Quick summary

A combination cold/allergy medication that relieves congestion, thins mucus, and reduces allergy symptoms.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 28, 2026Editorial policy

Key facts at a glance

RxNorm
1007364
Generic
Brompheniramine / Guaifenesin / Phenylephrine
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Temporary relief of nasal and sinus congestion, chest congestion, and symptoms associated with allergies, common cold, or respiratory infections such as runny nose, sneezing, and itchy/watery eyes.

Brompheniramine blocks histamine to reduce allergic reactions; guaifenesin thins and loosens mucus in the airways to ease coughing; phenylephrine constricts blood vessels in the nasal passages to reduce swelling and congestion.

May cause drowsiness; avoid alcohol and operating machinery until you know how it affects you. Consult a healthcare provider before use if you have high blood pressure, heart disease, thyroid disorders, diabetes, glaucoma, or urinary problems. Do not use with MAO inhibitors. Keep out of reach of children.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy