Brompheniramine / Guaifenesin / Phenylpropanolamine
This combination medication contains an antihistamine (brompheniramine), expectorant (guaifenesin), and decongestant (phenylpropanolamine). It is used to temporarily relieve symptoms of the common cold, allergies, and hay fever, including nasal congestion, sinus pressure, cough, and chest congestion associated with mucus.
A combination cold and allergy medication that relieves congestion, cough, and related symptoms through its antihistamine, expectorant, and decongestant components.
Key facts at a glance
- RxNorm
- 820128
- Generic
- Brompheniramine / Guaifenesin / Phenylpropanolamine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Used for temporary relief of cold, allergy, and hay fever symptoms including nasal and sinus congestion, postnasal drip, throat irritation, cough, and chest congestion. Helps loosen and thin mucus in the airways.
Brompheniramine blocks histamine receptors to reduce sneezing, itching, and runny nose; guaifenesin thins and loosens mucus in the respiratory tract making it easier to clear; phenylpropanolamine constricts blood vessels in the nasal passages to reduce swelling and congestion.
May cause drowsiness - avoid operating machinery or driving until you know how it affects you. Avoid alcohol and other sedating medications. Not recommended for children without medical supervision. Note: Phenylpropanolamine was withdrawn from the US market in 2000 due to stroke risk; product availability varies by country. Consult a healthcare provider before use, especially if you have hypertension, heart disease, thyroid disorders, or glaucoma.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy