Brompheniramine / Hydrocodone / Phenylephrine
This combination medication is used to treat symptoms of the common cold, flu, allergies, and other respiratory illnesses. It contains an antihistamine (brompheniramine) to reduce runny nose and sneezing, an opioid cough suppressant (hydrocodone) to control coughing, and a decongestant (phenylephrine) to relieve nasal congestion. This medication is typically prescribed when a patient experiences both cough and significant nasal congestion that requires multiple therapeutic approaches.
A combination cold/cough medication that addresses congestion, coughing, and runny nose through three different active ingredients.
Key facts at a glance
- RxNorm
- 607163
- Generic
- Brompheniramine / Hydrocodone / Phenylephrine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Relief of cough and cold symptoms including nasal congestion, runny nose, sneezing, itchy/watery eyes, and cough associated with upper respiratory infections, allergies, or sinusitis.
Brompheniramine blocks histamine H1 receptors to reduce allergic symptoms; hydrocodone suppresses the cough reflex in the brain; phenylephrine constricts blood vessels in the nasal passages to reduce swelling and congestion.
Contains an opioid (hydrocodone) with risk of dependence, sedation, and respiratory depression. May cause drowsiness; avoid operating machinery or driving. Not recommended for children under 18 years old. Should not be used with alcohol, sedatives, or other CNS depressants. Consult healthcare provider before use if pregnant, breastfeeding, or taking other medications.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy