Brompheniramine / Hydrocodone / Pseudoephedrine
Brompheniramine/Hydrocodone/Pseudoephedrine is a combination medication used to relieve multiple symptoms of upper respiratory conditions, including cough, nasal congestion, and allergy symptoms. The three active ingredients work together to address different aspects of cold and allergy symptoms simultaneously. This medication is typically prescribed when patients experience concurrent symptoms that benefit from antihistamine, cough suppressant, and decongestant therapy.
A combination antihistamine, cough suppressant, and decongestant used to treat multiple cold and allergy symptoms at once.
Key facts at a glance
- RxNorm
- 404780
- Generic
- Brompheniramine / Hydrocodone / Pseudoephedrine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
This medication is used to treat symptoms of upper respiratory allergies, common cold, and hay fever, including cough, nasal congestion, sinus congestion, sneezing, runny nose, and itchy/watery eyes. It is typically prescribed when multiple symptoms are present that require treatment with different classes of medications.
Brompheniramine blocks histamine H1 receptors to reduce allergic symptoms; Hydrocodone suppresses the cough reflex in the brain; Pseudoephedrine constricts blood vessels in the nasal passages to reduce swelling and congestion. Together, they provide multi-symptom relief by targeting different pathways involved in cold and allergy responses.
Hydrocodone is an opioid that carries risks of dependence, drowsiness, and respiratory depression. This medication should not be used in children under 12 years old. Patients should avoid operating machinery or driving until they know how the medication affects them. Pseudoephedrine may increase blood pressure and heart rate. Alcohol and other CNS depressants should be avoided. This medication should only be used as prescribed and for the shortest duration necessary.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy