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Brompheniramine / Phenylpropanolamine

Published: July 27, 2026Updated: August 28, 2026

Brompheniramine/Phenylpropanolamine is a combination antihistamine and decongestant used to temporarily relieve symptoms of the common cold, allergies, and hay fever. The medication addresses both nasal congestion through the decongestant component and allergic symptoms like runny nose, sneezing, and itchy eyes through the antihistamine component.

Quick summary

An antihistamine-decongestant combination for temporary relief of cold and allergy symptoms.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 28, 2026Editorial policy

Key facts at a glance

RxNorm
214325
Generic
Brompheniramine / Phenylpropanolamine
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Temporarily relieves symptoms associated with the common cold, influenza, hay fever, and other upper respiratory allergies, including runny nose, sneezing, itchy/watery eyes, and nasal congestion.

Brompheniramine blocks histamine H1 receptors to reduce allergic symptoms, while phenylpropanolamine constricts blood vessels in the nasal passages to reduce swelling and congestion.

May cause drowsiness; avoid driving or operating machinery until you know how it affects you. Use with caution in patients with hypertension, heart disease, diabetes, or thyroid disorders. Not recommended for children under 6 years old. Note: Phenylpropanolamine was withdrawn from the US market in 2000 due to associated stroke risk; availability varies by country.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy