Buclizine / Hydroxyzine / Niacin
This multi-ingredient medication combines two antihistamines (buclizine and hydroxyzine) with niacin (vitamin B3) to stimulate appetite and promote weight gain. It is primarily used for patients experiencing appetite loss, malnutrition, or cachexia who need nutritional support. The antihistamine components work on appetite-regulating pathways, while niacin supports overall metabolic function.
An appetite stimulant combination used for weight management in patients with appetite loss or malnutrition.
Key facts at a glance
- RxNorm
- 1007060
- Generic
- Buclizine / Hydroxyzine / Niacin
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Used to stimulate appetite and promote weight gain in patients with reduced appetite, malnutrition, or cachexia. May also be used for nausea associated with motion sickness in some formulations.
The antihistamine ingredients (buclizine and hydroxyzine) act on H1 receptors and may influence appetite centers in the brain, while niacin (vitamin B3) supports metabolic processes and overall nutritional status.
May cause drowsiness due to antihistamine effects. Use with caution in elderly patients and those with liver or kidney impairment. Avoid alcohol and other CNS depressants. Niacin may cause flushing. Not recommended during pregnancy without medical supervision.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy