Buflomedil / Diosmin
This multi-ingredient medication combines bufomedil, a peripheral vasodilator, with diosmin, a flavonoid with venotonic properties. The combination is primarily used for managing chronic venous disorders and associated symptoms like heaviness and discomfort in the legs. The two agents work synergistically to improve venous tone and microcirculation.
A combination vasodilator and venotonic agent used for venous circulation disorders.
Key facts at a glance
- RxNorm
- 813460
- Generic
- Buflomedil / Diosmin
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of chronic venous insufficiency, leg heaviness, pain, and discomfort associated with venous disorders. May also be used for hemorrhoidal symptoms in some formulations.
Bufomedil acts as an alpha-adrenergic blocker causing peripheral vasodilation, while diosmin strengthens venous walls and reduces capillary permeability. Together they aim to improve blood flow and reduce venous stasis.
May cause gastrointestinal upset, dizziness, or headache. Contraindicated in patients with bleeding disorders or recent hemorrhage. Bufomedil has been withdrawn from several markets due to cardiac safety concerns—consult current regional availability. Avoid alcohol and prolonged standing.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy