Buprenorphine and Naloxone
Bunavail is a brand-name sublingual film medication used to treat opioid use disorder as part of a complete treatment program that includes counseling and behavioral therapy. It combines buprenorphine, a partial opioid agonist that helps reduce cravings and withdrawal symptoms, with naloxone to deter misuse.
Bunavail is a sublingual medication combining buprenorphine and naloxone used to treat opioid dependence.
Key facts at a glance
- RxNorm
- 1542391
- Generic
- Bunavail
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Bunavail is indicated for the treatment of opioid use disorder (OUD). It is typically used as medication-assisted treatment (MAT) for individuals dependent on opioids, as part of a comprehensive treatment program that includes counseling and psychosocial support.
Bunavail contains two active ingredients: buprenorphine (a partial mu-opioid receptor agonist) and naloxone (an opioid antagonist). Buprenorphine helps reduce opioid cravings and withdrawal symptoms by partially activating opioid receptors. Naloxone, when taken sublingually as prescribed, has minimal effect due to poor absorption, but if injected, it blocks opioid effects and can precipitate withdrawal, thereby deterring misuse.
Bunavail is a Schedule III controlled substance and carries risks of dependence, misuse, and abuse. Common side effects may include headache, nausea, vomiting, constipation, and sweating. It should be prescribed by healthcare providers certified under the DEA and should be stored safely out of reach of children. Patients should not discontinue use abruptly without medical supervision.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed September 3, 2026. · Read our editorial policy