Buserelin Acetate
Buserelin acetate is a synthetic analogue of gonadotropin-releasing hormone (GnRH) that acts as a potent inhibitor of sex hormone production. It is primarily used in the treatment of hormone-sensitive cancers, endometriosis, and for assisted reproductive technologies. By initially stimulating and then suppressing the pituitary gland, it reduces the production of sex hormones such as testosterone and estrogen.
Buserelin acetate is a GnRH analogue that suppresses sex hormone production, used for hormone-sensitive cancers, endometriosis, and fertility treatments.
Key facts at a glance
- RxNorm
- 42569
- Generic
- Buserelin Acetate
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of advanced prostate cancer, endometriosis, central precocious puberty, hormone receptor-positive breast cancer, and used in assisted reproductive technology protocols for controlled ovarian stimulation.
Acts as a GnRH agonist; initial administration causes a surge in luteinizing hormone (LH) and follicle-stimulating hormone (FSH), followed by sustained suppression of these hormones, leading to decreased testosterone and estrogen production.
May cause an initial testosterone flare in male patients; commonly associated with hot flashes, decreased libido, and bone density loss with prolonged use. Contraindicated in pregnancy. Available as nasal spray, injection, or implant formulations. Regular monitoring of hormone levels is recommended during treatment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy