Buspirone
Buspirone is an anxiolytic medication primarily used to treat generalized anxiety disorder (GAD). Unlike benzodiazepines, it is non-sedating and has a low risk of dependence, making it suitable for long-term anxiety management.
Buspirone is a non-benzodiazepine anxiety medication that works on serotonin receptors to reduce anxiety symptoms without causing sedation or dependence.
Key facts at a glance
- ATC
- N05BE01
- RxNorm
- 1827
- Generic
- Buspirone
- Class
- atc-n05
- Brands
- Buspar, Bucapsol
- Availability
- rx
- Pregnancy
- B
- Lactation
- safe
- Routes
- oral
- Forms
- capsule, tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Buspirone is FDA-approved for the treatment of generalized anxiety disorder (GAD) in adults. It may also be used off-label for other anxiety-related conditions when appropriate.
Buspirone works as a partial agonist at serotonin 5-HT1A receptors in the brain. This action helps regulate serotonin activity, which plays a key role in mood and anxiety regulation.
Unlike benzodiazepines, buspirone is not habit-forming and does not cause significant sedation or cognitive impairment. It typically takes 2-4 weeks to achieve full therapeutic effect, so it is not suitable for acute anxiety relief. Common side effects include dizziness, headache, and nausea.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy