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Butabarbital / Ephedrine / Guaifenesin / Theophylline

Published: July 27, 2026Updated: August 28, 2026

This multi-ingredient medication combines a barbiturate sedative with bronchodilators and an expectorant to manage respiratory symptoms. It is primarily used for treating asthma, bronchitis, and other conditions involving airway constriction and excessive mucus production. The combination targets both the smooth muscle relaxation needed for breathing and the removal of respiratory secretions.

Quick summary

A combination respiratory medication used for asthma and bronchitis that includes sedatives, bronchodilators, and expectorants.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 28, 2026Editorial policy

Key facts at a glance

RxNorm
690824
Generic
Butabarbital / Ephedrine / Guaifenesin / Theophylline
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Treatment of asthma, bronchitis, and related respiratory conditions involving bronchoconstriction and excessive mucus production. May be used for symptomatic relief in COPD and other obstructive airway diseases.

Theophylline and ephedrine act as bronchodilators by relaxing airway smooth muscle. Guaifenesin thins and loosens mucus in the airways. Butabarbital provides mild sedation to reduce anxiety and restlessness associated with respiratory distress.

Barbiturates like butabarbital carry risks of dependence and should be used cautiously. Theophylline has a narrow therapeutic window requiring monitoring. This combination may interact with other medications affecting the heart or nervous system. Not typically used as first-line therapy in modern practice.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy