Butabarbital / Methamphetamine
This multi-ingredient medication combines a barbiturate sedative (butabarbital) with a stimulant (methamphetamine). Such combinations are uncommon in modern medical practice due to the opposing effects of sedatives and stimulants. Methamphetamine is a Schedule II controlled substance with significant abuse potential.
A sedative-stimulant combination medication rarely used in contemporary practice due to the opposing effects of its components.
Key facts at a glance
- RxNorm
- 1007323
- Generic
- Butabarbital / Methamphetamine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Not typically prescribed in modern medicine. Methamphetamine alone has limited use for ADHD and narcolepsy, while butabarbital was formerly used for anxiety and insomnia. The combination lacks standard therapeutic applications.
Butabarbital is a central nervous system depressant that enhances GABA activity, producing sedation. Methamphetamine is a stimulant that increases dopamine and norepinephrine release. The combination creates opposing effects.
This is a Schedule II controlled substance due to methamphetamine's high abuse potential. Barbiturate-stimulant combinations are uncommon due to unpredictable effects and safety concerns. Use requires careful medical supervision. Methamphetamine has significant cardiovascular risks and addiction potential.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy