Butoconazole Nitrate
Butoconazole Nitrate is an antifungal medication used to treat vaginal yeast infections caused by Candida species. It belongs to the azole class of antifungals and works by inhibiting the growth of fungus in the vaginal area. This medication is available by prescription only and is typically administered as a vaginal cream or suppository.
Butoconazole Nitrate is a prescription antifungal used to treat vaginal yeast infections.
Key facts at a glance
- RxNorm
- 47464
- Generic
- Butoconazole Nitrate
- Class
- pin-variant
- Brands
- Gynazole-1
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Butoconazole Nitrate is used to treat vulvovaginal candidiasis, commonly known as a vaginal yeast infection. It is effective against infections caused by Candida albicans and other Candida species.
Butoconazole works by inhibiting the enzyme lanosterol 14-alpha-demethylase, which is essential for synthesizing ergosterol—a critical component of fungal cell membranes. This disruption weakens the fungal cell wall, preventing growth and replication.
Patients should complete the full course of treatment even if symptoms improve. Common side effects may include vaginal burning, itching, or irritation. Those with known sensitivity to azole antifungals should avoid this medication. Pregnant patients should consult their healthcare provider before use.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy