Butorphanol
Butorphic is a brand-name nasal spray medication that combines butorphanol, an opioid analgesic with mixed agonist-antagonist properties, with benzocaine, a local anesthetic. It is primarily used for the short-term management of moderate to severe pain when rapid relief is needed. This medication is available by prescription only due to its opioid component.
Butorphic is a prescription nasal spray combining an opioid analgesic with a local anesthetic for short-term relief of moderate to severe pain.
Key facts at a glance
- RxNorm
- 1310923
- Generic
- Butorphic
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Used for short-term management of moderate to severe pain, particularly where rapid onset of pain relief is desired. Due to its nasal spray formulation, it may be chosen when oral medications are not suitable.
Contains butorphanol, a mixed opioid agonist-antagonist that works by binding to opioid receptors in the brain to alter pain perception. The benzocaine component provides local anesthetic effects. Onset typically occurs within 15-30 minutes of administration.
Contains an opioid component, so carries risks of dependence, abuse, and addiction. Common side effects may include drowsiness, dizziness, nausea, and nasal congestion. Should not be used by patients with certain respiratory conditions or those taking other opioid medications. Use is generally limited to short-term treatment due to potential for dependence.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed September 3, 2026. · Read our editorial policy