Butriptyline Hydrochloride
Butriptyline Hydrochloride is a tricyclic antidepressant (TCA) used primarily to treat major depressive disorder. It works by inhibiting the reuptake of neurotransmitters, particularly norepinephrine, helping to restore chemical balance in the brain and improve mood.
Butriptyline Hydrochloride is an older tricyclic antidepressant used to treat depression by affecting neurotransmitter levels in the brain.
Key facts at a glance
- RxNorm
- 324004
- Generic
- Butriptyline Hydrochloride
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Primarily prescribed for major depressive disorder. May also be used for certain anxiety disorders and chronic pain conditions in some cases.
Functions as a norepinephrine reuptake inhibitor with weaker effects on serotonin. Also exhibits anticholinergic and antihistamine properties that contribute to its therapeutic and side effect profiles.
Due to its anticholinergic effects, common side effects include dry mouth, constipation, and urinary retention. Requires careful dose titration and monitoring, especially in patients with cardiac conditions. Like other TCAs, it carries risks of sedation and requires caution when combined with other CNS depressants.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy